产品货号:
JN1733
中文名称:
重组人MASP1(甘露聚糖结合凝集素丝氨酸蛋白酶1)
英文名称:
Recombinant Human Mannan-Binding Lectin Serine Protease 1
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的His20-Arg728在C端含有His标签。
MASP1质量控制:>95%(还原性SDS-PAGE)
MASP1制剂:液体
MASP1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于MASP1:
Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.
相关搜索:重组人MASP1(甘露聚糖结合凝集素丝氨酸蛋白酶1)
MASP1质量控制:>95%(还原性SDS-PAGE)
MASP1制剂:液体
MASP1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于MASP1:
Mannan-Binding Lectin Serine Protease 1 (MASP-1) belongs to the peptidase S1 family. MASP1 contains two CUB domains, one EGF-like domain, one peptidase S1 domain and two Sushi (CCP/SCR) domains. MASP1 is primarily expressed in liver. MASP1 involved in the lectin pathway of the complement, performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. MASP1 is synthesized as a zymogen and activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. MASP1 is not directly involved in complement activation but may act as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP2. MASP1 is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. MASP1 is inhibited by SERPING1 and A2M.
相关搜索:重组人MASP1(甘露聚糖结合凝集素丝氨酸蛋白酶1)